HOSPITAL VITAL BRAZIL



Chefe da Unidade:

Dr. França, Francisco Oscar Siqueira, PhD



Pesquisadores da Unidade:

Dr. Medeiros, Carlos Roberto de , MD    

Dr. Malaque, Ceila Maria Sant'Ana, MD    

Dr. Novaes, Christina Terra Gallafrio, MD

Dr. Fan, Hui Wen, PhD   

Dr. Cardoso, João Luiz Costa, MD   

Dr. Prado, José Carlos Lopes, PhD    

Dr. Risk, José Yamin, MD

Dr. Haddad Jr, Vidal, PhD– médico colaborador

Objetivo Geral da Unidade:

Prestar assistência médica aos pacientes picados por animais peçonhentos.
Desenvolver estudos clínicos e epidemiológiscos relacionados aos acidentes humanos causados por animias peçonhentos
Promover programas de treinamento a profissionais da saúde e guias para o diagnóstico e tratamento dos acidentes humanos causados por animais peçonhentos.

Linhas de Pesquisa Atuais:

Terapêutica para os acidentes humanos causados por animais peçonhentos como serpentes, aranhas, escorpiões e lagartas: eficácia de diferentes tratamentos tem sido avaliadas através de ensaios clínicos com o objetivo de diminuir a morbidade e letalidade causadas pelos envenenamentoe e reduzir reações aos antivenenos.

Publicações:

Duarte MR, Almeida-Santos SM, Cardoso JLC. An attack on a human by a green anaconda ( Eunectes murinus ). Bull Chicago Herp Soc 35 (7): 164, 2000.

Boechat ALR, Paiva CS, França FOS, dos Santos MC. Heparin-antivenom association: differential neutralization effctiveness in Bothrops atrox and Bothrops erythromelas envenoming. Rev Inst Med Trop São Paulo 43(1): 7-14, 2001

Benvenuti LA, Douetts KV, Cardoso JLC. Myocardial necrosis after envenomation by the scorpion Tityus serrulatus . Trans R Soc Trop Med Hyg 96: 275-6, 2002.

França FOS, Barbaro KC, Abdulkader RC. Rhabdomyolysis in presumed viscero-cutaneous loxoscelism: report of two cases. Trans R Soc Trop Med Hyg 96: 287-90, 2002.

Haddad Jr V, Da Silveira FL, Cardoso JLC, Morandini AC. A report of 49 cases of cnidarian envenoming from southeastern Brazilian coastal waters. Toxicon 40: 1445-1450, 2002.

Malaque CMS, Castro-Valencia JE, CARDOSO JLC, França FOS, Barbaro KC, Fan HW. Clinical and epidemiological features of definitive and presumed loxoscelism in Sao Paulo, Brazil. Rev Inst Med Trop Sao Paulo 44: 139-43, 2002.

Barretto OC, Satake M, Nonoyama K, Cardoso JL. The calcium-dependent protease of Loxosceles gaucho venom acts preferentially upon red cell band 3 transmembrane protein. Braz J Med Biol Res 36(3):309-13, 2003.

Benvenuti LA, Franca FO, Barbaro KC, Nunes JR, Cardoso JL. Pulmonary haemorrhage causing rapid death after Bothrops jararacussu snakebite: a case report. Toxicon 42(3):331-4, 2003.

Haddad Jr V, Martins IA, Makyama HM. Injuries caused by scorpionfishes (Scorpaena plumieri Bloch, 1789 and Scorpaena brasiliensis Cuvier, 1829) in the Southwestern Atlantic Ocean (Brazilian coast): epidemiologic, clinic and therapeutic aspects of 23 stings in humans. Toxicon 42:79-83, 2003.

Haddad Jr V, Sazima I. Piranhas attacks in Southeast of Brazil: epidemiology, natural history and clinical treatment with description of a bite outbreak. Wild Environ Med 14(4): 249-254, 2003.

Haddad Junior V, Pardal PP, Cardoso JL, Martins IA. The venomous toadfish Thalassophryne nattereri (niquim or miquim): report of 43 injuries provoked in fishermen of Salinopolis (Para State) and Aracaju (Sergipe State), Brazil. Rev Inst Med Trop São Paulo 45(4):221-3, 2003.

Pardal PP, Souza SM, Monteiro MR, Fan HW, Cardoso JL, Franca FO, Tomy SC, Sano-Martins IS, de Sousa-e-Silva MC, Colombini M, Kodera NF, Moura-da-Silva AM, Cardoso DF, Velarde DT, Kamiguti AS, Theakston RD, Warrell DA. Clinical trial of two antivenoms for the treatment of Bothrops and Lachesis bites in the north eastern Amazon region of Brazil. Trans R Soc Trop Med Hyg 98(1):28-42, 2004.

Jorge MT, Malaque C, Ribeiro LA, Fan HU, Cardoso JLC, Nishioka AS, Sano-Martins IS, França FOS, Kamiguti AS, Theakston RDG, Warrel DA. Failure of chloramphenicol prophylaxis to reduce the frequency of abscess formation as a complication of envenoming by Bothrops snakes in Brazil: a double-blind randomized controlled trial. Trans R Soc Trop Med Hyg 98:529-534, 2004. .

Haddad Jr V, Garrone Neto D, Paula Neto JB, Marques FPL, Bárbaro KC. Freshwater stingrays: study of epidemiologic, clinic and therapeutic aspects based in 84 envenomings in humans and some enzymatic activities of the venom. Toxicon 43 (3): 287-294, 2004.

Haddad Jr V . Cutaneous infections and injuries caused by traumatic and
venomous animals which occurred in domestic and commercial aquariums in Brazil: a study of 18 cases and an overview of the theme. Anais Brasileiros de
Dermatologia 79 (2): 157-167, 2004.

Haddad Jr V . Skin manifestations caused by Brazilian traumatic, allergenic and venomous plants: main species, therapeutic and preventive measures. Journal of Venomous Animals and Toxins including Tropical Diseases 10 (3): 199-206, 2004.

Miot HA, Baptistella RF, Batista KA, Volpato DEC, Augusto LST, Madeira NG, Haddad Jr V, Miot LDB. Comparative study of the topical efectiveness of the Andiroba oil ( Carapa guianensis ) and DEET 50% as repellent for Aedes sp . Revista do Instituto de Medicina Tropical de São Paulo 46 (5): 253-256, 2004.

Haddad Jr V, Gadig OBF. The spiny dogfish ( cação-bagre ):description of an envenoming in a fisherman, with taxonomic and toxinologic comments on the Squalus gender. Toxicon 46 (1); 108-110, 2005

Haddad Jr V, Assunção MC, Mello RC, Duarte MR. A Fatal Attack caused by a Lowland Tapir ( Tapirus terrestris ) in Southeastern Brazil. Wilderness and Enviromental Medicine 16 (2): 97-100, 2005.

Garrone Neto D, Cordeiro R, Haddad Jr V . Acid entes do trabalho em pescadores artesanais da região do Médio Rio Araguaia, Tocantins, Brasil.
Cadernos de Saúde Pública 21 (3): 795-803, 2005.

Capítulos de livros

França FOS, Fan HW, Malaque CMS, Cardoso JLC. O Paciente Vítima de Animais Peçonhentos I. Acidentes Ofídicos e Soroterapia. In: Velasco IT, Karam JA, Cruz Neto LM, Caramez MPR, Gattaz MD (eds) Propedêutica na Emergência. Ed. Atheneu, São Paulo, cap. 29, 347-358, 2003.

França FOS, Fan HW, Malaque CMS, Cardoso JLC. O Paciente Vítima de Animais Peçonhentos II. Aranhas, Escorpiões e Insetos. In: Velasco IT, Karam JA, Cruz Neto LM, Caramez MPR, Gattaz MD (eds) Propedêutica na Emergência. Ed. Atheneu, São Paulo, cap. 29, 347-358, 2003.

Haddad Jr V. O Paciente Vítima de Animais Peçonhentos III. Emergências Provocadas por Animais Marinhos e Fluviais. In: Velasco IT, Karam JA, Cruz Neto LM, Caramez MPR, Gattaz MD (eds) Propedêutica na Emergência. Ed. Atheneu, São Paulo, cap. 29, 347-358, 2003.

Medeiros CR, França FOS, Cardoso JLC, Fan HW, Malaque CMS. Acidentes Provocados por Animais Peçonhentos. In: Paes Jr J, Giavina-Bianchi P (eds) Diagnóstico e Terapêutica das Urgências Médicas. Ed. Roca, São Paulo, cap.38, 360-380, 2003.

Livros

Cardoso JLC, França FOS, Fan HW, Malaque CMS, Haddad Jr V. Animais Peçonhentos no Brasil. Biologia, Clínica e Terapêutica dos Acidentes. Ed. Sarvier/Fapesp, São Paulo, 2003, 469 p.

Pardal PP, Souza SM, Monteiro MR, Fan HW, Cardoso JL, Franca FO, Tomy SC, Sano-Martins IS, de Sousa-e-Silva MC, Colombini M, Kodera NF, Moura-da-Silva AM, Cardoso DF, Velarde DT, Kamiguti AS, Theakston RD, Warrell DA. Clinical trial of two antivenoms for the treatment of Bothrops and Lachesis bites in the north eastern Amazon region of Brazil. Trans R Soc Trop Med Hyg. 2004, 98(1):28-42.

Jorge MT, Malaque C, Ribeiro LA, Fan HU, Cardoso JLC, Nishioka AS, Sano-Martins IS, França FOS, Kamiguti AS, Theakston RDG, Warrel DA. Failure of chloramphenicol prophylaxis to reduce the frequency of abscess formation as a complication of envenoming by Bothrops snakes in Brazil: a double-blind randomized controlled trial. Trans R Soc Trop Med Hyg. 2004, 98:529-534. .